Description This highly acclaimed textbook is written specifically for students of medicine and related health science subjects. It progresses from a review of general pathology principles and disease mechanisms through detailed discussions of the pathologic entities associated with each organ system. Nearly 700 full-color photographs and pathology slides bring the content to life. The fifth edition features extensive updates throughout to reflect the latest discoveries in cellular and molecular pathology, and offers a web site that presents self-assessment material and illustrated clinical case studies. . Contents perfectly matches needs on medical students. . Very clinical approach matches integrated courses. Extensive International Advisory Board validates contents. . Each organ system chapter begins with a brief review of normal structure and function, emphasizing aspects that are important to an understanding of the subsequently discussed disease processes. . Offers a superb collection of clinical photographs, histopathology images, and graphics, approximately 700 in all, that richly depict the appearance of both healthy and diseased tissues. . New co-editor, Dr Simon Cross. . Structure of chapters revised to make the book much easier to use during courses that are problem- or case-based. . Several new contributors and re-written chapters. . Expanded Internationa Advisory Board.